Lucy Webb was last seen in the area of Narborough Road South, near Fosse Park, last Tuesday evening (9 July).
Officers are appealing for anyone who may have seen a missing 16-year-old girl to come forward.
Lucy Webb was last seen in the area of Narborough Road South, near Fosse Park, last Tuesday evening (9 July).
It has since been confirmed she travelled to London and was seen arriving at Euston railway station last Wednesday (10 July).
Leicestershire Police, said: "Lucy may have travelled elsewhere in London and is known to visit Lewisham and Harrow. She is also known to use the railway network and may have travelled to another part of the UK.
"When she was last seen in Leicestershire – and when she arrived in London – Lucy was wearing a bright green jumper, black body warmer, a pink mini skirt and grey trainers.
"Anyone with any information regarding Lucy’s whereabouts is asked to call 101 quoting incident 698 of 9 July."
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Lucy Webb (Image released by Leicestershire Police)