The eight month year-old received thousands of nominations for the award during her battle with Leukaemia.
On Sunday (25th April) her father, former Coventry City footballer, Ashley Cain, who lives in Nuneaton posted to social media to confirm baby Azaylia had passed away from cancer.
In a Facebook post, Pride of Britain said, "Our thoughts are with Ashley and Safiyya who have sadly lost their beautiful daughter Azaylia after such a brave fight. She truly was an inspiration. RIP #likklelion"
Our thoughts are with Ashley and Safiyya who have sadly lost their beautiful daughter Azaylia after such a brave fight. She truly was an inspiration. RIP #likklelion
Posted by The Pride of Britain Awards on Sunday, April 25, 2021
The blood cancer charity, Anthony Nolan, also took to social media to pay tribute.
As a result of Azaylia's appeal, 36,000 people have reportedly joined the charity's stem-cell register.
We were devastated to learn the news that lovely little Azaylia Cain passed away on Saturday.
— Anthony Nolan (@AnthonyNolan) April 26, 2021
Azaylia’s appeal has to date inspired over 36,000 people to join the Anthony Nolan stem cell register - a number so high, none of us could have anticipated it. (1/10) pic.twitter.com/rdau52h7Oa